Common sense about antibiotic use during pregnancy

　　Pregnant women with infectious disease Antibiotics may also be used. It is currently known that during pregnancy, most antibiotics are harmful to the embryo and fetus Both have adverse effects, therefore, the impact on both should be clearly understood when selecting antibiotics.

　　Antibiotics used by pregnant women are generally divided into the following types: one is usable and causes little or no harm to the fetus;； Secondly, use it with caution, as it may cause damage to the fetus, but when necessary, it can be used in a short course and in a small dose. ； The third type is forbidden, it will cause serious damage to the fetus and must not be used. The commonly used antibiotics are explained below:

　　Antibiotics used throughout pregnancy : Penicillins, cephalosporins, erythromycin and keratin. These four antibiotics are used during pregnancy and generally do not cause adverse reactions to the fetus. A penicillin allergy test must be done before using penicillin drugs to avoid drug allergic reactions.

　　Antibiotics to be used with caution throughout pregnancy: Aminoglycosides include streptomycin, kanamycin, gentamicin, and amikacin. They should be used with caution because they can damage fetal kidney function and hearing. If it is really necessary to use it, it should be in small doses and for a short course of treatment.

　　Antibiotics contraindicated in certain stages of pregnancy : Chloramphenicol, pyrimethamine, rifampicin, sulfonamides, etc. are prohibited in early pregnancy, that is, within 12 weeks of pregnancy, and chloramphenicol, pyrimethamine, sulfonamides, sulfonamides, and other drugs are prohibited after 28 weeks of pregnancy. Chloramphenicol, rifampicin, and pyrimethamine can cause fetal urethral and ear canal malformations, deafness, limb malformations, hydrocephalus, stillbirth, and neonatal death. Sulfa drugs can cause neonatal jaundice and hemolytic anemia , Furandidine can cause hemolysis in newborns. 》》》 Pregnant woman appears7Be careful with these symptoms

　　Antibiotics contraindicated throughout pregnancy: 1. Polymyxin, colistin, etc., are harmful to the kidneys and nerve It has systemic toxic effects and can cross the placenta and affect the fetus. 2. Tetracycline is a typical teratogen. In the early stages of pregnancy, it chelates with calcium salts to prevent calcium salts from entering cartilage and bones, leading to fetal limb dysplasia and small limb deformities. ； It inhibits fetal bone growth in the second trimester, causing fetal congenital cataracts, abnormal development of deciduous teeth, and yellow deciduous teeth. ； Late pregnancy can cause tetracycline deposition in deciduous teeth and bones and turn them yellow, and can lead to hepatic steatosis in pregnant women, so it is contraindicated in pregnant women. 3. Metronidazole (also called metronidazole) is contraindicated by pregnant women because it has a teratogenic effect on the fetus. 4. Amphotericin B, griseofulvin, etc. are highly toxic to the nervous system, blood, liver and kidneys. Griseofulvin has teratogenic effects on the fetus and may also cause miscarriage.