The best treatment for cavernous sclerosis

Peyronie's disease with cavernous sclerosis can be improved through drug therapy, physical therapy, local injection therapy, surgical treatment and lifestyle adjustments. Non-invasive treatment is preferred when the disease is mild, and surgical intervention should be considered for patients with longer disease duration or severe symptoms.

1. Drug treatment:

Mild to moderate patients can choose oral drugs such as colchicine, L-carnitine or vitamin E. Colchicine reduces plaque hardness by inhibiting fibrosis process ； L-carnitine improves local microcirculation ； Vitamin E acts as an antioxidant to slow down tissue damage. It is necessary to choose a medication plan according to individual conditions under the guidance of a doctor and avoid adjusting the dosage on your own.

2. Physical therapy:

Extracorporeal shock wave therapy and traction devices are commonly used physical interventions. Low-intensity shock waves can promote plaque softening and improve penile curvature ； The traction device corrects deformation through mechanical force and is used for 30-60 minutes every day. Physical therapy needs to last 3-6 months and is suitable for patients with early-stage lesions that are not calcified.

3. Local injection treatment:

Collagenase Clostridium histolytica injection or local injection of glucocorticoid can directly act on fibrous plaque. Collagenase breaks down abnormal collagen deposits, and glucocorticoids reduce inflammation. Injection treatment needs to be performed by a professional physician and repeated every 4-6 weeks. Side effects such as local hematoma may occur.

4. Surgical treatment:

Those with severe curvature >60 degrees or dyspareunia should consider plaque removal + graft repair or penile prosthesis implantation. Surgery can correct the deformity but may affect erectile function. Postoperative rehabilitation training is required. It is suitable for patients whose disease duration exceeds 12 months and for whom conservative treatment is ineffective.

5. Lifestyle adjustments:

Smoking cigarettes and limiting alcohol consumption can slow down the progression of the disease, and smoking can aggravate vascular endothelial damage. Moderate aerobic exercise such as swimming and brisk walking can improve blood circulation, and avoid cycling and other exercises that compress the perineum. Eat a balanced diet to increase your intake of antioxidants, such as blueberries, tomatoes and other anthocyanin-rich foods.

It is recommended that patients avoid local trauma stimulation and use gentle positions during sexual intercourse. Regular penile ultrasound examinations are performed to monitor plaque changes, and those with diabetes or hypertension need to control underlying diseases. Psychological counseling can help relieve anxiety, and partners' participation in treatment can improve the recovery effect. When the pain is obvious in the acute stage, cold compress can be used, but it is forbidden to massage the hardened area by yourself. If erectile dysfunction or abnormal urination occurs, a follow-up visit should be made in time to adjust the treatment plan.