Enid The lack of ovarian follicle growth can be dealt with by adjusting lifestyle, drug ovulation induction, acupuncture-assisted treatment, surgical intervention and other assisted reproductive technologies. Ovarian follicle development disorder may be related to endocrine disorders, ovarian hypofunction, polycystic ovary syndrome and other factors, and usually manifests as irregular menstruation, infertility and other symptoms.
1. Adjust your lifestyle
Maintaining a regular schedule helps regulate hypothalamic-pituitary-ovarian axis function. Ensure 7-8 hours of sleep every day and avoid staying up late. Do moderate aerobic exercise such as brisk walking, swimming, etc., 3-5 times a week, 30 minutes each time. The diet requires a balanced intake of high-quality protein, vitamin E and zinc, such as deep-sea fish, nuts, whole grains, etc. Reducing stress can be achieved through methods such as meditation and deep breathing. People with abnormal weight should control their BMI between 18.5-24.
2. Drugs to induce ovulation
Clomiphene capsule is a commonly used ovulation induction drug, suitable for patients with hypothalamic amenorrhea. It promotes follicle growth by competitively binding to estrogen receptors. As an aromatase inhibitor, letrozole tablets can reduce estrogen levels and stimulate follicular development, which is especially suitable for patients with polycystic ovary syndrome. Urinary gonadotropin injection can directly stimulate the proliferation of ovarian granulosa cells, and follicle development needs to be monitored through B-ultrasound during use. Ovarian hyperstimulation syndrome may occur during medication and requires close follow-up.
3. Acupuncture auxiliary treatment
Traditional Chinese medicine believes that follicle development disorders are related to insufficient kidney essence and imbalance of Chong and Ren. Acupuncture at Guanyuan, uterus, Sanyinjiao and other acupoints can regulate gonadal axis function and improve ovarian blood flow. Moxibustion at Shenque point can warm and nourish kidney yang and promote follicle maturation. Treatment needs to start on the 5th day of the menstrual cycle, once every other day, and continue for 10-12 times. Research shows that acupuncture can improve the ovulation-stimulating effects of clomid. During the treatment period, no cold or cold irritating foods are allowed.
4. Surgical intervention
Laparoscopic ovarian drilling is suitable for patients with polycystic ovary syndrome who have failed to respond to drug treatment. It uses laser or electrocoagulation to create 4-10 tiny holes on the ovarian surface to reduce androgen levels. Wedge resection of the ovaries is now rarely used and is reserved for selected cases. The probability of natural pregnancy within 6 months after surgery is high. Surgical risks include premature ovarian failure, pelvic adhesions, etc. Folic acid supplementation is required after surgery to prevent fetal neural tube defects.
5. Assisted reproductive technology
In vitro fertilization-embryo transfer is suitable for patients with fallopian tube factors and ovulation disorders. Multiple follicles can be obtained through controlled super-stimulation of ovulation. Intracytoplasmic sperm injection technology can solve the problem of severe male infertility. In vitro maturation culture of immature eggs is suitable for patients with low ovarian response. Genetic screening is required before embryo implantation. The live birth rate is closely related to the woman's age, and can reach 50% under the age of 35. The treatment cycle must strictly follow the arrangements of the reproductive center.
It is recommended to record the basal body temperature curve to monitor ovulation and use ovulation test strips to detect the urine LH peak. Eat foods containing omega-3 fatty acids such as salmon and flax seeds 2-3 times a week. Avoid exposure to environmental endocrine disruptors such as bisphenol A. During drug treatment, six items of sex hormones were reviewed every month, and endometrial thickness was monitored by ultrasound. If there is still no pregnancy after 3-6 cycles, salpingography should be considered to rule out other infertility factors. Maintaining a positive attitude can help improve treatment outcomes.
