Estrogen is a female Hormone, produced by the ovaries and placenta. The adrenal cortex also produces small amounts of estrogen. After female children enter puberty, the ovaries begin to secrete estrogen to promote vaginal and Uterus , the development of fallopian tubes and ovaries themselves, and at the same time, endometrial hyperplasia produces menstruation. Estrogen can also promote the accumulation of subcutaneous fat and make the body plump; Breast hyperplasia , the nipples and areola become darker in color, and produce sexual desire; promote the retention of sodium and water in the body, and the deposition of calcium in the bones, etc.
When the follicles begin to develop, they only secrete a small amount of estrogen; on the 7th day of menstruation, the amount of estrogen secreted by the follicles increases rapidly, reaches a peak before ovulation, and decreases slightly after ovulation. About 1-2 days after ovulation, the corpus luteum begins to secrete estrogen, causing the estrogen in the blood circulation to gradually rise again (Note: it is the function of luteinizing hormone). When the corpus luteum matures about 7-8 days after ovulation, the second peak of estrogen in the blood circulation is formed, which is lower than the first peak before ovulation.
What are the consequences of a lack of estrogen?
The latest research has found that there are more than 400 estrogen receptors in the female body, mainly distributed in the uterus, vagina, breasts, pelvis (ligaments and connective tissue) and skin , bladder, urethra, bones and brain. Estrogen has such a wide range of effects. No wonder many people exclaim about the physical and psychological changes that occur throughout a girl's pubertal development - "the eighteen changes of a yellow-haired girl." In turn, when women enter menopause, as estrogen decreases significantly, the tissues, organs, and systems where these more than 400 receptors are located undergo changes. This can explain menopause Why do post-menopausal women undergo a series of physiological and psychological changes? If more serious systemic symptoms occur around menopause, menopausal syndrome will form.
Pharmacological effects of estrogen
1 Direct effect on the ovary, estrogen can stimulate follicle development; indirect effect, the blood concentration of estrogen can promote or inhibit the release of gonadotropins, thereby indirectly affecting ovarian function.
2 Fallopian tube estrogen can accelerate the speed of eggs in the fallopian tubes.
3 Uterine estrogen has a significant promoting effect on the metabolism of endometrium and smooth muscle.
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